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Publication available in: PDF (176 KB) Related Resources Osteogenesis Imperfecta Fast Facts Osteogenesis Imperfecta Overview OI and Exercise OI in Adulthood Talking to Your Doctor About OI Partner Resources Be An Active Member of Your Health Care Team (FDA) Questions Are the Answer: Get More Involved in Your Health Care (AHRQ) Talking with Your Doctor (NIA) Conversando con su Médico (NIA) Sea Miembro Activo del Equipo de Cuidados de la Salud (FDA) Print-Friendly Page January 2012 Type I OI Osteogenesis imperfecta Issues: Type Is Understanding the Mildest Form of Osteogenesis Imperfecta

Osteogenesis imperfecta (OI) is a genetic disorder characterized by bones that break easily. OI is highly variable. Its signs and symptoms range from mild to severe. In addition to fractures (broken bones), people with OI sometimes have muscle weakness, loose joints (joint laxity), curvature of the spine (scoliosis), brittle teeth (dentinogenesis imperfecta), and hearing loss.

Olivopontocerebellar Atrophy

Osteogenesis imperfecta Issues: Maintaining Health During the Adult Years

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